Jarrow Formulas, Natural SAM-e (S-Adenosyl-L-Methionine) 400, 400 mg, 30 Enteric-Coated Tablets

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Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 30
 Amount Per Tablet%DV
S-Adenosyl Methionine (from 800 mg of SAM-e tosylate disulfate)400 mg
Daily Value not established.
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Description

  • Full Potency
  • In Foil Blister Pack
  • Natural
  • pH Sensitive
  • Food Grade
  • EnteroGuard Coating
  • S-Adenosyl Methionine
  • 400 mg (Net Yield) SAM-e from 800 mg SAM-e tosylate Disulfate
  • Highest Concentration of Active S,S Form
  • Enteric-Coated Tablets
  • Net Yield: 400 Mg SAM-e
  • Gluten Free
  • Vegan
  • Dietary Supplement

Promotes:

  • Joint Strength
  • Liver Detoxification
  • Mood and Brain Function

Jarrow Formulas SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Contains More of the Active S,S Form

Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S)  SAM-e, the highest active level available.

SAM-e has been clinically shown to have the following benefits:

Joint Strength

SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-E metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.

Brain Metabolism

SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).

Liver

SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase), which are components of the body’s endogenous antioxidant network and important for liver function, including phase II detoxification.

EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resist stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

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